Zafrul Hasan

Zafrul has received his PhD in Medical Sciences and his focus was on Anti-HIV immunity from Kumamoto University, Kumamoto, Japan, on 2012. He successfully completed his two posdocs in Japan and research focus was Alzhiemer disease and Autoimmunity in mice model. Now-a-days Dr. Zafrul serving BMB department at SUST as faculty member with others. Hasan completed his MS and BSc in “Dept. of Biochemistry and Molecular Biology” University of Dhaka, Dhaka, Bangladesh. After MS, Hasan worked as a Research Officer in Virology laboratory, icddr,b, Dhaka and the primary responsibility was to run experiments for syphilis, HIV and hepatitis (B and C) for the annual Serological Surveillance of HIV that was conducting for the Government of Bangladesh. Exploring new places, new cultures, making friends, driving, watching movies, are the few things Zafrul like most.

Education:

• PhD Medical Sciences (Anti-HIV immunity (2012), Kumamoto University, Kumamoto, Japan.
• Master of Science in Biochemistry and Molecular biology (2003), University of Dhaka, Dhaka, Bangladesh.
• Bachelor of Science in Biochemistry and Molecular biology (2002), University of Dhaka, Dhaka, Bangladesh .
• Higher Secondary School Certificate Examination (1998), Dhaka College, Dhaka, Bangladesh.
• Secondary School Certificate Examination (1996), Sara Maroari High School, Iswardi, Bangladesh.

Research Interests:

• Advanced molecular Immunology
• Neurobiology
• Epidemiology
• Active Research Project
• JunB protein as a candidate biomarker in cancer diagnosis and its therapeutical implication funded by SUST Research centre.

Awards & Recognition:

• Junior Research Associate (JRA) supporting grant (250,000 yen) 2012, Center for AIDS Research, Kumamoto University; Global GCOE program, Japan.
• Support project of conference travel expenses for graduate student’s scheme (60,000 yen) 2011, Japanese Society for Immunology, 2011; Kumamoto University.
• Global Health Travel Award Scholarship 2011, Keystone Symposium, Whistler, BC Canada (HIV Evolution, Genomics and Pathogenesis, X7), funded by Bill & Melinda Gates Foundation.
• Junior Research Associate (JRA) supporting grant (400,000 yen) 2011, Center for AIDS Research, Kumamoto University; Global GCOE program, Japan.
• Global Health Travel Award Scholarship 2010, Keystone Symposium, Calgary (Banff), Canada (HIV vaccines X5), funded by Bill & Melinda Gates Foundation.
• Junior Research Associate (JRA) supporting grant (400,000 yen) 2010, Center for AIDS Research, Kumamoto University; Global GCOE program, Japan.
• Junior Research Associate (JRA) supporting grant (500,000 yen) 2009, Center for AIDS Research, Kumamoto University; Global GCOE program, Japan.
• Monbukagakusho scholarship 2008, Ministry of Education, Culture, Sports, Science and Technology Japan, MEXT.

Selected Publications

• Hasan Z, Koizumi SI, Sasaki D, Yamada H, Arakaki N, Fujihara Y, Okitsu S, Shirahata H, Ishikawa H. JunB is essential for IL-23-dependent pathogenicity of Th17 cells. Nat Commun. 2017 May 30. PMID: 28555647.
• Elahi M, Hasan Z, Motoi Y, Matsumoto SE, Ishiguro K, Hattori N.Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice. J Alzheimers Dis. 2016 Feb 25. PMID: 26923011.
• Elahi M, Motoi Y, Matsumoto SE, Hasan Z, Ishiguro K, Hattori N. Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice. Neurosci Lett. 2016 Jan 1. PMID: 26592481.
• Meribe SC, Hasan Z, Mahiti M, Mwimanzi F, Toyoda M, Mori M, Gatanaga H, Kikuchi T, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Ueno T. Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection. Arch Virol. 2015 Jun 10. PMID: 26060058.
• Hasan Z, Doreen Kamori, and Ueno T. Role of host immune responses in sequence variability of HIV-1 Vpu. World J Immunol 2014 July 27. ISSN 2219-2824
• Hasan Z, Carlson JM, Gatanaga H, Le AQ, Brumme CJ, Oka S, Brumme ZL, Ueno T.　Minor contribution of HLA class I-associated selective pressure to the　variability of HIV-1 accessory protein Vpu. Biochem Biophys Res Commun. 2012 May 4. PMID: 22503975.
• Mwimanzi P, Hasan Z, Hassan R, Suzu S, Takiguchi M, Ueno T. Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages. Retrovirology. 2011 Jun 22. PMID: 21696586.
• Mwimanzi P, Hasan Z, Tokunaga M, Gatanaga H, Oka S, Ueno T. Naturally arising HIV-1 Nef variants conferring escape from cytotoxic T lymphocytes influence viral entry co-receptor expression and susceptibility to superinfection. Biochem Biophys Res Commun. 2010 Dec 17. PMID: 21093412.
• Motozono C, John J. Miles, Hasan Z, Gatanaga H, Stanley C. Meribe, David A. Price, Oka S, Andrew K. Sewell, and Ueno T. CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope. PLoS One. 2013 Jun 17. PMID: 23799076.
• Rahman M, Hassan ZM, Hasan Z, Saiada F, Banik S, Faruque AS, Delbeke T, Matthijnssens J, Van Ranst M, Azim T. Sequence analysis and evolution of group B rotaviruses. Virus Res. 2007 Feb 12. PMID: 17292993.