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Alliance Manchester Business School

Biography

Alliance Manchester Business School
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Overview

My area of research is complex disease genetics. This applies to conditions where multiple genes interplay with environmental triggers.

I use both genetic and functional approaches to further the understanding of:

 (i) The commonest inflammatory arthritis to affect children under 16 years – Juvenile Idiopathic Arthritis.

(ii) Changes that arise with weight variation    a.  Obesity

                                                                         b.  Bariatric surgery

                                                                         c. Diabetes (T2DM, T1D, GDM)

(iii) Inflammatory pathologies, especially where variation in steroid sensitivity is a factor (eg SLE).

Biography

Rachelle Donn MB ChB PhD

Expertise in: Molecular Genetics and Functional Genomics.

Main Research interests:

1) Genetics of complex diseases (Juvenile Idiopathic Arthritis, Diabetes, Systemic Lupus Erythematosus)

2) Genetic basis of drug response (Steroids)

3) Network analysis of complex genetic diseases

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