Hua Huang

Education

• Doctor of Philosophy (Ph.D.) NUS gruduate school (2007 — 2010)
• Attachment Max Planck Institute for Medical Research (2009 — 2009)
• Bachelor of Science in Life-science National University of Singapore (2003 — 2007)

Companies

• Research Assisant Professor National University of Singapore (2018)
• Research fellow National University of Singapore (2011)

Publications

• Huang, H., Tan, B.Z., Shen, Y., Tao, J., Jiang, F., Sung, Y.Y., Ng, C.K., Raida, M., Kohr, G., Higuchi, M. et al. (2012) RNA editing of the IQ domain in Ca(v)1.3 channels modulates their Ca(2)(+)-dependent inactivation. Neuron. 73, 304-316.(impact factor: 13.974)
• Huang H., Wang J., Soong T.W. (2013) Splicing and Editing to Customize CaV Channel Structures for Optimal Neural Function. In: Stephens G., Mochida S. (eds) Modulation of Presynaptic Calcium Channels. Springer, Dordrecht. ISBN 978-94-007-6333-3 (book chapter contribution)
• Huang, H., Yu, D. and Soong, T.W. (2013) C-terminal alternative splicing of CaV1.3 channels distinctively modulates their dihydropyridine sensitivity. Mol Pharmacol. 84, 643-653. (impact factor: 4.128)
• Huang, H., Ng, C.Y., Yu, D., Zhai, J., Lam, Y. and Soong, T.W. (2014) Modest CaV1.342-selective inhibition by compound 8 is beta-subunit dependent. Nat Commun. 5, 448. (impact factor: 11.329)
• Li, G., Wang, J., Liao, P., Bartels, P., Zhang, H., Yu, D., Liang, M.C., Poh, K.K., Yu, C.Y., Jiang, F., Yong, T.F., Wong, Y.P., Hu, Z., Huang, H., Zhang, G., Galupo, M.J., Bian, J.S., Ponniah, S., Trasti, S.L., See, K., Foo, R., Hoppe, U.C., Herzig, S., and Soong, T.W. (2017) Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic. Proc Natl Acad Sci USA. 114, E4288-E4295 (impact factor: 9.661)
• Bartels, P., Yu, D., Huang, H., Hu, Z., Herzig, S., Soong, T.W. (2018) Alternative splicing at N-terminus and domain I modulates Cav1.2 inactivation and surface expression. Biophys J. 2018 May 8;114(9):2095-2106. doi: 10.1016/j.bpj.2018.03.029. (impact factor: 3.632)
• Huang, H*., Kapeli, K., Jin, W., Wong, Y.P., Arumugam, T.V., Koh, J.H., Srimasorn, S., Mallilankaraman, K., Chua, J.J.E, Yeo G.W., Soong, T.W.* (2018) Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9. Nucleic Acids Res. 2018 May 4. doi: 10.1093/nar/gky348. (impact factor: 10.162, *co-corresponding author)
• Mei Q, Bansal A, Jayakumar MKG, Zhang Z, Zhang J, Huang H, Yu D,Ramachandra CJA, Hausenloy DJ, Soong TW, Zhang Y. Manipulating energy migration within single lanthanide activator for Switchable up conversion emissions towards bidirectional photoactivation. Nat Commun. 2019 Sep 27;10(1):4416. (impact factor: 11.329)
• Huang, H*., Tay, S. H., Ng, W., Ng, S. Y. & Soong, T. W. Targeting novel human transient receptor potential ankyrin 1 splice variation with splice-switching antisense oligonucleotides. Pain. 162, 2097-2109 (2021). (impact factor: 6.029, *corresponding author)