Tobias Loddenkemper

As a pediatrician, pediatric neurologist, and clinical neurophysiologist, with specific training in seizure monitoring and treatment, I spend approximately 40% of my time in investigation, 20% in direct clinical care, 10% in teaching activities, and 30% in significant supporting activities. My early research experience as a resident and fellow included observational and interventional studies on clinical seizure manifestations and treatment. Following my 2008 appointment as Assistant in Neurology at Boston Children’s Hospital, I expanded my research to include circadian variation of seizures and used this information to develop a patient-oriented medication treatment schedule. My research is focused on identifying the factors that determine epileptic encephalopathies and status epilepticus as well as functional outcome later in life. Repetitive seizures and epileptic encephalopathy can impair development, plasticity and cognitive function of eloquent areas including language and memory. Seizure frequency reduction and seizure freedom, in particular after epilepsy surgery, have been shown to improve neurocognitive and developmental outcome. By identifying biomarkers that indicate predictors of cerebral damage and developmental outcome in epileptic encephalopathies and status epilepticus, we intend to reduce the occurrence of brain damage and later developmental disabilities and aim to identify novel therapeutic approaches.

Education

Medical School Westfalische Wilhelms-Universitat 1999, Munster, Germany

Internship Pediatrics Cleveland Clinic 2004, Cleveland, OH

Residency Neurology Westfalische Wilhelms-Universitat Munster, Germany

Residency Pediatrics Cleveland Clinic Cleveland, OH

Residency Child Neurology Cleveland Clinic 2008, Cleveland, OH

Fellowship Epilepsy & Clinical Neurophysiology Cleveland Clinic 2003, Cleveland, OH

Companies

• Professor of Neurology Harvard Medical School (2019)
• Pediatric Neurologist and Epileptologist Boston Children's Hospital (2008)
• Associate Professor of Neurology Harvard Medical School (2013 — 2019)
• Assistant Professor of Neurology Harvard Medical School (2008 — 2013)
• Pediatric Neurology Resident Cleveland Clinic (2003 — 2008)
• Epilepsy and Clinical Neurophysiology Fellow Cleveland Clinic (2000 — 2003)