Sam Au

Sam Au joined Imperial in 2017 as a lecturer (assistant professor equivalent) in the Department of Bioengineering. His research group uses lab-on-chip microdevices to gain insights into the influence of cell and tissue biomechanics on the progression of diseases such as metastatic cancer. The goal is to translate these findings into novel therapeutic strategies to sabotage key elements of disease development and progression. Sam also serves as Associate Scientific Advisor for Science Translational Medicine.

Prior to Imperial, Sam was a Tosteson Postdoctoral Fellow in the lab of Professor Mehmet Toner at Harvard Medical School and Massachusetts General Hospital where he developed microfluidic models of the microvasculature to investigate how circulating tumour cell clusters traversed the narrow vessels of the body. Sam obtained a PhD in Biomedical Engineering while in Professor Aaron Wheeler's group at the University of Toronto in 2013 and a BSc in Chemical Engineering in 2008.

Publications

Journals

• Kawara S, Cunningham B, Bezer J, et al., 2023, Capillary-Scale Hydrogel Microchannel Networks by Wire Templating., Small
• Au SH, 2023, Circulating Tumor Cell Cluster Sorting by Size and Asymmetry., Methods Mol Biol, Vol:2679, Pages:15-23
• Ashby JF, Schmidt J, Kc N, et al., 2022, Microfluidic T cell selection by cellular avidity., Advanced Healthcare Materials, Vol:11, ISSN:2192-2640, Pages:1-14
• Varotsos Vrynas A, Perea Paizal J, Bakal C, et al., 2021, Arresting metastasis within the microcirculation, Clinical & Experimental Metastasis, Vol:38, ISSN:0262-0898, Pages:337-342
• Suba K, Hansen B, Ruhela A, et al., 2022, Functional imaging of pancreatic islets on a microfluidic chip platform, WILEY, ISSN:0742-3071