Karen Miller

Karen K. Miller, MD is a clinician in the Neuroendocrine Clinical Center and a faculty member in the Neuroendocrine Unit at the Massachusetts General Hospital, and a Professor of Medicine at Harvard Medical School. She is an NIH-funded clinical researcher who studies the neuroendocrine regulation of body composition and brain function, with a focus on hormone deficiency and excess states, including growth hormone and androgens, on body composition and brain function. Awards in recognition of her work have included The Endocrine Society International Award for Excellence in Published Clinical Research in The Journal of Clinical Endocrinology and Metabolism in 2006. She is the author of more than 100 peer-reviewed publications and has served on the editorial board of the Journal of Clinical Endocrinology and Metabolism.

Departments, Centers, & Programs:

• Neuroendocrinology

Clinical Interests:

• Acromegaly
• Amenorrhea
• Cushing's syndrome
• Hypopituitarism
• Pituitary tumors

Research & Publications

Research Summary

Dr. Miller is an NIH-funded clinical researcher who studies the neuroendocrine regulation of body composition and brain function, with a focus on hormone deficiency and excess states, including growth hormone and androgens, on body composition and brain function. Her research interests include hypopituitarism, acromegaly, androgen deficiency and replacement therapy in women and growth hormone deficiency and replacement therapy.

Publications

• Miller KK et al. Androgen deficiency in women with hypopituitarism. J Clin Endocrinol Metab. 2001; 86:561-7.
• Miller KK et al. Effects of testosterone replacement in androgen-deficient women with hypopituitarism: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2006; 91:1683-90.
• Miller KK et al. Growth hormone deficiency after treatment of acromegaly: a randomized, placebo-controlled study of growth hormone replacement. J Clin Endocrinol Metab. 2010; 95(2):567-77.
• Dichtel LE et al. Overweight/obese adults with pituitary disorders require lower peak growth hormone cut-off values on glucagon stimulation testing to avoid overdiagnosis of growth hormone deficiency. J Clin Endocrinol Metab. 2014 (in press).

Medical Education

• MD, Johns Hopkins University School of Medicine
• Residency, Brigham and Women's Hospital
• Fellowship, Massachusetts General Hospital

American Board Certifications

• Endocrinology, Diabetes and Metabolism, American Board of Internal Medicine