David Leong

Dr. David Tai Leong is an Associate Professor at the Department of Chemical and Biomolecular Engineering, National University of Singapore (NUS). He obtained his PhD in Biology and Bachelor in Chemical Engineering from NUS and received his post-doctoral training at the Howard Hughes Medical Institute at the University of Pennsylvania. His research interests span across fundamental understanding of biological effects of nanomaterials to their applications in nanomedicine, biosensing and nanotoxicology.

Education

• Postdoctoral training University of Pennsylvania School of Medicine (2007 — 2008)
• PhD National University of Singapore (2002 — 2006)
• Adv Dip (Edn) Nanyang Technological University Singapore (1998 — 1999)
• B Eng National University of Singapore (1994 — 1998)

Companies

• Associate Professor (Tenured) Chemical and Biomolecular Engineering, National University of Singapore (2017)
• Asst Professor National University of Singapore (2010 — 2016)
• Lee Kuan Yew Fellow National University of Singapore (2008 — 2010)
• Postdoctoral Fellow Howard Hughes Medical Institute, University of Pennsylvania (2007 — 2008)
• Graduate student National University of Singapore (2002 — 2006)

Research Interests

• Fluid Mechianics of Metastasis
• Cellular Engineering
• Bioengineering
• Cancer Biology

Selected Publications

Setyawati M.I.; Tay C.Y.; Chia S.L.; Goh S.L.; Fang, W.; Neo, M.J.; Chong, H.C.; Tan, S.M.; Loo, S.C.; Ng, K.W.; Xie, J.P.; Ong. C.N.; Tan, N.S.; Leong, D.T*. TiO2 nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin. NATURE Communications, 4, 1673, 2013. (IF 10)

Yuan, X.; Setyawati, M.I.; Tan, A.S.; Ong, C.N.; Leong, D.T.* and Xie, J.* “Highly Luminescent Silver Nanoclusters with Tunable Emissions: Cyclic Reduction-Decomposition Synthesis and Antimicrobial Property”, NATURE Publishing Group Asia Materials 2013, DOI: 10.1038/am.2013.3 (IF 9).

Luo, Z.; Yuan, X.; Yu, Y.; Zhang, Q.; Leong, D.T.; Lee, J.Y. and Xie, J* “From Aggregation-Induced Emission of Au(I)-Thiolate Complexes to Ultra-bright Au(0)@Au(I)-Thiolate Core-Shell Nanoclusters”, Journal of the American Chemical Society 2012, 134, 16662-16670 (IF 11).

Setyawati, M.I.; Fang, W.; Chia, S.L.; Leong, D.T.*. Nanotoxicology of common metal oxide based nanomaterials: their ROS-y and non-ROS-y consequences. Asia Pacific Journal of Chemical Engineering. 2012. DOI: 10.1002/apj.1680.

Wu, Y.L.; Putcha, N.; Ng, K.W.; Leong, D.T.; Lim, C.T.; Loo, S.C.; Chen, X. Biophysical Responses upon the Interaction of Nanomaterials with Cellular Interfaces. Accounts of Chemical Research. 2012. DOI: 10.1021/ar300046u. (IF 21)