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Carmela Abraham

Professor of Biochemistry and Medicine School of Medicine at Boston University

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  • Boston University

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Biography

Boston University

Dr. Carmela Abraham completed her undergraduate degree at Tel Aviv University, Israel. She earned her PhD degree in Neurobiology from Harvard University. She joined the Boston University School of Medicine’s Departments of Medicine and Biochemistry in 1989 as an Assistant Professor and has since been promoted to Professor.

Dr. Abraham’s research interests are focused on the etiology of Alzheimer’s disease and the role of the Amyloid Precursor Protein (APP) and Abeta peptide in the development of the disease. She also studies enzymes that break down the toxic Abeta peptide as a means to therapeutically clear the brain of this peptide. Genetic and molecular studies indicate that Abeta initiates the neurodegenerative aspects of Alzheimer’s disease.

Dr. Abraham is the recipient of The Neuroscience Education and Research Foundation Award for an Outstanding Promise as a Young Alzheimer Investigator (1990). Moreover she is the recipient of the highest awards from the Alzheimer’s Association – The Zenith Award (1994) and the Temple Award (1999). She is a member of the Society for Neuroscience, American Society for Neurochemistry, American Association of Neuropathologists, New York Academy of Science, International Society for Amyloidosis, American Academy for the Advancement of Science, among others

 

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Cases

We Are on the Path to Reversing the Damage Caused by Alzheimer’s

December 6, 2017

Futurism Carmela Abraham For more than three decades, experts have understood that a gene variant called ApoE4 can greatly increase the risks of the degenerative brain condition known as Alzheimer’s disease by up to 12 times… Expert quote: “There is much evidence that amyloid beta is an initiating factor in a cascade of events that leads […]

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Shot of Klotho Boosts Memory In Aging and Diseased Mice

August 15, 2017

Alzforum quoting Carmela Abraham, School of Medicine “Talk about instant gratification. According to an August 8 paper in Cell Reports, injecting a fragment of the protein klotho markedly improves memory and motor function in mice…” Expert quote: “It’s one more step toward proving that klotho is correlated with cognitive improvement.” View full article.   

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Possible Anti-Aging Brain Therapy Shows Promise in Mice

August 8, 2017

Scientific American quoting Carmela Abraham, School of Medicine “Clotho, one of the Three Fates of Greek mythology, carried the weighty responsibility of spinning the thread of human life…” Expert quote: “What’s amazing here is that something you inject into the belly has such effects on cognition without increasing levels of klotho in the brain.” View […]

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Alzheimer’s Cure: New Compound Acts As Protein-Blocker

October 26, 2015

HealthAIM Carmela Abraham, School of Medicine Amyloid beta is a type of sticky protein that clump together as groups in the brain and end up choking the nerve cells… View full article referencing expert Carmela Abraham  

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Mouse brain cells live long and prosper

February 25, 2013

Science News Carmela Abraham, School of Medicine Mouse brain cells scamper close to eternal life: They can actually outlive their bodies… Expert quote: “The question is: Can neurons live longer if we prolong our life span?” View full article

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