Thomas Müller-Späth

Thomas Müller-Späth, Dr. sc. ETH, Dipl.-Ing., a founder, has more than 10 years of R&D and operational experience in the biopharmaceutical industry in Germany, Switzerland and the USA. Thomas is the co-inventor of several patents and has published numerous articles in journals. Besides his operational duties, Thomas serves to consult customers in technical business development.

Thomas holds a COO position at ChromaCon AG, Switzerland, and is one of the founders of the company where he started as Chief Scientifi c O¬ cer. He studied chemical engineering at the Technical University of Hamburg, Germany, and at the University of California, Berkeley (USA). Thomas gained further R&D experience at Bayer Healthcare in Berkeley, CA (USA), and Beiersdorf AG, Hamburg (GER). He obtained his PhD in multicolumn technology for the purification of proteins at the Swiss Federal Institute of Technology (ETH Zurich) in the group of Professor Morbidelli in 2008, where he is also active as a senior scientist. He is inventorof several patents and has authored numerous articles on continuous chromatography for biopharmaceuticals. Thomas frequently presents at international conferences as an invited speaker and also co-chairs workshops on continuous chromatography for the ETH Zurich.

Publications

• Muller-Spath T, Aumann L, Morbidelli M. 2009. Role of Cleaning-in-Place in the purification of mAb supernatants using continuous cation exchange chromatography, Separation Science and Technology 44 (1): 1-26.
• Muller-Spath T, Aumann L, Melter L, Strohlein G, Morbidelli M. 2008. Chromatographic Separation of three Monoclonal Antibody variants using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP), Biotechnology and Bioengineering 100 (6): 1166-1177.