Laszlo Vutskits

Research in our laboratory is focusing on the impact of general anesthetics on the developing central nervous system as well as on elucidating the cellular and molecular mechanisms underlying these effects. These investigations are motivated by the fact that millions of infants and young children receive anesthesia every year worldwide and perioperative neuromorbidity is several folds higher in these populations compared to older age groups. Since general anesthetics act on a wide variety of ligand-gated ionotropic, and therefore are powerful modulators of neuronal activity, they may indeed induce lasting changes in immature neuronal networks. Therefore, we specifically aim to elaborate the issues of how and to what extent these drugs induce morpho-functional changes in developing neural networks during the brain growth spurt. To achieve these goals, we use a combination of biochemical, electrophysiological and live imaging techniques to study the developmental stage-dependent influence of general anesthetics on the establishment of GABAergic and glutamatergic synaptic contacts during the assembly of neuronal circuitry in the immature brain.

Scientific Articles

• SZMUK, Peter et al. An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study. In: Paediatric Anaesthesia, 2019, vol. 29, n° 1, p. 59-67. doi: 10.1111/pan.13544
• BUHRE, Wolfgang et al. European Society of Anaesthesiology Task Force on Nitrous Oxide: a narrative review of its role in clinical practice. In: British Journal of Anaesthesia, 2019, vol. 122, n° 5, p. 587-604. doi: 10.1016/j.bja.2019.01.023
• VUTSKITS, Laszlo, CULLEY, Deborah J. GAS, PANDA, and MASK: No Evidence of Clinical Anesthetic Neurotoxicity!. In: Anesthesiology, 2019, vol. 131, n° 4, p. 762-764. doi: 10.1097/ALN.0000000000002863
• STERPENICH, Virginie et al. Increased reactivity of the mesolimbic reward system after ketamine injection in patients with treatment-resistant major depressive disorder. In: Anesthesiology, 2019, vol. 130, n° 6, p. 923-935. doi: 10.1097/ALN.0000000000002667
• LIN, Nan et al. Perspectives on dexmedetomidine use for neurosurgical patients. In: Journal of Neurosurgical Anesthesiology, 2019, vol. 31, n° 4, p. 366-377. doi: 10.1097/ANA.0000000000000554
• VUTSKITS, Laszlo, CLARK, J David, KHARASCH, Evan D. Reporting laboratory and animal research in anesthesiology: the importance of sex as a biologic variable. In: Anesthesiology, 2019, vol. 131, n° 5, p. 949-952. doi: 10.1097/ALN.0000000000002945
• BUHRE, Wolfgang et al. Response to comments on 'The European Society of Anaesthesiology Task Force review on the place of nitrous oxide in current clinical practice' (Br J Anaesth 2019; 122:587-604). In: British Journal of Anaesthesia, 2019, vol. 123, n° 4, p. e482-e483. doi: 10.1016/j.bja.2019.06.021
• YUAN, Ian et al. Statistical analysis plan for "an international multicenter study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery". In: Paediatric Anaesthesia, 2019, vol. 29, n° 3, p. 243-249. doi: 10.1111/pan.13589
• VIALE, Beatrice et al. Transient deregulation of canonical Wnt signaling in developing pyramidal neurons leads to dendritic defects and impaired behavior. In: Cell Reports, 2019, vol. 27, n° 5, p. 1487-1502.e6. doi: 10.1016/j.celrep.2019.04.026
• VUTSKITS, Laszlo, SALL, J W, JEVTOVIC-TODOROVIC, V. A poisoned chalice: the heritage of parental anaesthesia exposure. In: British Journal of Anaesthesia, 2018, vol. 121, n° 2, p. 337-339. doi: 10.1016/j.bja.2018.05.013
• OLBRECHT, Vanessa A. et al. An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia. In: Anesthesiology, 2018, vol. 128, n° 1, p. 85-96. doi: 10.1097/ALN.0000000000001920
• DISMA, Nicola et al. Anesthesia and the developing brain: A way forward for laboratory and clinical research. In: Paediatric Anaesthesia, 2018, vol. 28, n° 9, p. 758-763. doi: 10.1111/pan.13455
• VIRTANEN, Mari et al. Development of inhibitory synaptic inputs on layer 2/3 pyramidal neurons in the rat medial prefrontal cortex. In: Brain Structure and Function, 2018, vol. 223, n° 4, p. 1999-2012. doi: 10.1007/s00429-017-1602-0
• VIDAL, Sonia et al. Efficacy and Safety of a Rapid Intravenous Injection of Ketamine 0.5 mg/kg in Treatment-Resistant Major Depression: An Open 4-Week Longitudinal Study. In: Journal of Clinical Psychopharmacology, 2018, vol. 38, n° 6, p. 590-597. doi: 10.1097/JCP.0000000000000960
• VUTSKITS, Laszlo. General Anesthetics to Treat Major Depressive Disorder: Clinical Relevance and Underlying Mechanisms. In: Anesthesia and Analgesia, 2018, vol. 126, n° 1, p. 208-216. doi: 10.1213/ANE.0000000000002594
• STRICKER, Paul A et al. Pediatric perioperative outcomes group: Defining core outcomes for pediatric anesthesia and perioperative medicine. In: Paediatric Anaesthesia, 2018, vol. 28, n° 4, p. 314-315. doi: 10.1111/pan.13354
• VUTSKITS, Laszlo, SNEYD, J R. Quest for new drugs: a way to solve anaesthesia neurotoxicity? In: British Journal of Anaesthesia, 2018, vol. 120, n° 4, p. 619-621. doi: 10.1016/j.bja.2018.01.024
• VUTSKITS, Laszlo. SmartTots: Quo Vadis? In: Anesthesia and Analgesia, 2018, vol. 126, n° 4, p. 1124-1126. doi: 10.1213/ANE.0000000000002891
• VUTSKITS, Laszlo, SALL, Jeffrey W. Targeting Microglia: A New Avenue for Anesthesia Neuroprotection after Brain Injury? In: Anesthesiology, 2018, vol. 129, n° 2, p. 232-234. doi: 10.1097/ALN.0000000000002272
• RODIEUX, Frédérique et al. When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children. In: Frontiers in Pharmacology, 2018, vol. 9, p. 148. doi: 10.3389/fphar.2018.00148
• EFRON, Daryl, VUTSKITS, Laszlo, DAVIDSON, Andrew J. Can We Really Suggest that Anesthesia Might Cause Attention-deficit/Hyperactivity Disorder? In: Anesthesiology, 2017, p. 1. doi: 10.1097/ALN.0000000000001736
• PUSKARJOV, Martin et al. K-Cl Cotransporter 2?mediated Cl? Extrusion Determines Developmental Stage?dependent Impact of Propofol Anesthesia on Dendritic Spines. In: Anesthesiology, 2017, vol. 126, n° 5, p. 855-867. doi: 10.1097/ALN.0000000000001587
• VUTSKITS, Laszlo, SKOWNO, Justin. Perioperative Hypotension in Infants: Insights From the GAS Study. In: Anesthesia and Analgesia, 2017, vol. 125, n° 3, p. 719-720. doi: 10.1213/ANE.0000000000001959
• VUTSKITS, Laszlo. Predicting postoperative brain function from the blood: is there a role for biomarkers? In: British Journal of Anaesthesia, 2017, vol. 119, n° 2, p. 291-293. doi: 10.1093/bja/aex041
• VUTSKITS, Laszlo, SALL, J W. Reproducibility of science and developmental anaesthesia neurotoxicity: a tale of two cities. In: British Journal of Anaesthesia, 2017, vol. 119, n° 3, p. 451-452. doi: 10.1093/bja/aex221
• DAVIDSON, Andrew, VUTSKITS, Laszlo. The new FDA drug safety communication on the use of general anesthetics in young children: what should we make of it? In: Paediatric Anaesthesia, 2017, vol. 27, n° 4, p. 336-337. doi: 10.1111/pan.13122
• SORIANO, S G et al. Thinking, fast and slow: highlights from the 2016 BJA seminar on anaesthetic neurotoxicity and neuroplasticity. In: British Journal of Anaesthesia, 2017, vol. 119, n° 3, p. 443-447. doi: 10.1093/bja/aex238
• VUTSKITS, Laszlo, DAVIDSON, Andrew. Update on developmental anesthesia neurotoxicity. In: Current Opinion in Anaesthesiology, 2017, vol. 30, n° 3, p. 337-342. doi: 10.1097/ACO.0000000000000461
• QIU, Lin et al. Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats. In: Toxicological Sciences, 2016, vol. 149, n° 1, p. 121-133. doi: 10.1093/toxsci/kfv219
• VUTSKITS, Laszlo, XIE, Zhongcong. Lasting impact of general anaesthesia on the brain: mechanisms and relevance. In: Nature Reviews Neuroscience, 2016, vol. 17, n° 11, p. 705-717. doi: 10.1038/nrn.2016.128
• VUTSKITS, Laszlo. More Than Anyone Else: Preemies Need Good Analgesia. In: Anesthesiology, 2016, vol. 124, n° 4, p. 758-760. doi: 10.1097/ALN.0000000000001018
• LOEPKE, Andreas W., VUTSKITS, Laszlo. Reply to Hooijmans, Carlijn; Wever, Kimberley; Ritskes-Hoitinga, Merel; Scheffer, Gert Jan, regarding their comment ?The usefulness of systematic reviews of animal studies; shooting the messenger? In: Paediatric Anaesthesia, 2016, vol. 26, n° 8, p. 853-854. doi: 10.1111/pan.12958
• LOEPKE, Andreas W., VUTSKITS, Laszlo. What lessons for clinical practice can be learned from systematic reviews of animal studies? The case of anesthetic neurotoxicity. In: Paediatric Anaesthesia, 2016, vol. 26, n° 1, p. 4-5. doi: 10.1111/pan.12826
• DAVIDSON, Andrew J et al. Anesthesia and the developing brain: a way forward for clinical research. In: Paediatric Anaesthesia, 2015, vol. 25, n° 5, p. 447-52. doi: 10.1111/pan.12652
• HANSEN, Tom G, VUTSKITS, Laszlo. Anesthesia-related neurotoxicity and the developing brain:--do not overreact. A commentary. In: Acta Anaesthesiologica Belgica, 2015, vol. 66, n° 3, p. 63-65.
• OSTEROP, Samira et al. Developmental stage-dependent impact of midazolam on calbindin, calretinin and parvalbumin expression in the immature rat medial prefrontal cortex during the brain growth spurt. In: International Journal of Developmental Neuroscience, 2015, vol. 45, p. 19-28. doi: 10.1016/j.ijdevneu.2015.04.002
• VUTSKITS, Laszlo, SORIANO, Sulpicio G. Imaging the Progression of Anesthetic-induced Neurotoxicity: a Leap Toward Translational Relevance. In: Anesthesiology, 2015, vol. 123, n° 3, p. 497-498. doi: 10.1097/ALN.0000000000000763
• KARGARAN, Parichehr et al. Impact of propofol anaesthesia on cytokine expression profiles in the developing rat brain: a randomised placebo-controlled experimental in-vivo study. In: European Journal of Anaesthesiology, 2015, vol. 32, n° 5, p. 336-45. doi: 10.1097/EJA.0000000000000128
• KRZISCH, Marine et al. Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. In: Brain Structure and Function, 2015, vol. 220, n° 4, p. 2027-2042. doi: 10.1007/s00429-014-0768-y
• WEISS, Markus et al. Safe Anesthesia For Every Tot ? The SAFETOTS initiative. In: Current Opinion in Anaesthesiology, 2015, vol. 28, n° 3, p. 302-307. doi: 10.1097/ACO.0000000000000186
• SKOWNO, Justin et al. Staying away from the edge - cerebral oximetry guiding blood pressure management. In: Paediatric Anaesthesia, 2015, vol. 25, n° 7, p. 654-655. doi: 10.1111/pan.12698
• IBRAHIM, Rami Mossad et al. Systemic physiology and neuroapoptotic profiles in young and adult rats exposed to surgery: A randomized controlled study comprising four different anaesthetic techniques. In: International Journal of Developmental Neuroscience, 2015, vol. 45, p. 11-18. doi: 10.1016/j.ijdevneu.2015.04.351
• KANAVAKI, Aikaterini et al. Bronchial rupture after sled trauma in a 13-year-old boy. In: Annals of Thoracic Surgery, 2014, vol. 97, n° 1, p. 345. doi: 10.1016/j.athoracsur.2013.04.087
• VUTSKITS, Laszlo. Cerebral blood flow in the neonate. In: Paediatric Anaesthesia, 2014, vol. 24, n° 1, p. 22-29. doi: 10.1111/pan.12307
• LEE, Bradley H. et al. Early Exposure to Volatile Anesthetics Impairs Long-Term Associative Learning and Recognition Memory. In: PLOS ONE, 2014, vol. 9, n° 8, p. e105340. doi: 10.1371/journal.pone.0105340
• VUTSKITS, Laszlo. General anesthetics in brain injury: friends or foes? In: Current Pharmaceutical Design, 2014, vol. 20, n° 26, p. 4203-4210.
• VUTSKITS, Laszlo, PATEL, Piyush. Pushing the Standards Forward. In: Anesthesia and Analgesia, 2014, vol. 119, n° 5, p. 1029-1031. doi: 10.1213/ANE.0000000000000440
• FIUMELLI, Hubert et al. An ion transport-independent role for the cation-chloride cotransporter KCC2 in dendritic spinogenesis in vivo. In: Cerebral Cortex, 2013, vol. 23, n° 2, p. 378-88. doi: 10.1093/cercor/bhs027
• JEVTOVIC-TODOROVIC, V. et al. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. In: British Journal of Anaesthesia, 2013, vol. 111, n° 2, p. 143-151. doi: 10.1093/bja/aet177
• LACOH, C.- M. et al. General anaesthetics do not impair developmental expression of the KCC2 potassium-chloride cotransporter in neonatal rats during the brain growth spurt. In: British Journal of Anaesthesia, 2013, vol. 110, n° suppl 1, p. i10-i18. doi: 10.1093/bja/aet063
• KRZISCH, Marine et al. Propofol Anesthesia Impairs the Maturation and Survival of Adult-born Hippocampal Neurons. In: Anesthesiology, 2013, vol. 118, n° 3, p. 602-610. doi: 10.1097/ALN.0b013e3182815948
• RICCIO WICHT, Orbicia et al. Alpha2-adrenergic receptor activation regulates cortical interneuron migration. In: European Journal of Neuroscience, 2012, vol. 36, n° 7, p. 2879-87. doi: 10.1111/j.1460-9568.2012.08231.x
• VUTSKITS, Laszlo. Anesthetic-related neurotoxicity and the developing brain: shall we change practice? In: Pediatric Drugs, 2012, vol. 14, n° 1, p. 13-21. doi: 10.2165/11592840-000000000-00000
• VUTSKITS, Laszlo, DAVIS, Peter J., HANSEN, Tom G. Anesthetics and the developing brain: time for a change in practice? A pro/con debate. In: Paediatric Anaesthesia, 2012, vol. 22, n° 10, p. 973-980. doi: 10.1111/pan.12015
• ZGRAGGEN, Eloisa et al. Early postnatal migration and development of layer II pyramidal neurons in the rodent cingulate/retrosplenial cortex. In: Cerebral Cortex, 2012, vol. 22, n° 1, p. 144-57. doi: 10.1093/cercor/bhr097
• MASSA, Horace, LACOH, Claudia-Marvine, VUTSKITS, Laszlo. Effects of Morphine on the Differentiation and Survival of Developing Pyramidal Neurons During the Brain Growth Spurt. In: Toxicological Sciences, 2012, vol. 130, n° 1, p. 168-179. doi: 10.1093/toxsci/kfs234
• VUTSKITS, Laszlo. General Anesthesia. In: Anesthesia and Analgesia, 2012, vol. 115, n° 5, p. 1174-1182. doi: 10.1213/ANE.0b013e31826a1178
• RICCIO WICHT, Orbicia et al. New pool of cortical interneuron precursors in the early postnatal dorsal white matter. In: Cerebral Cortex, 2012, vol. 22, n° 1, p. 86-98. doi: 10.1093/cercor/bhr086
• KANAVAKI, Ino, VUTSKITS, Laszlo, RIMENSBERGER, Peter. Use of therapeutic surfactant lavage in a preterm infant with massive pulmonary hemorrhage. In: Clinics and Practice, 2012, vol. 2, n° 3. doi: 10.4081/cp.2012.e74
• BRINER, Adrian et al. Developmental Stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex. In: Anesthesiology, 2011, vol. 115, n° 2, p. 282-93. doi: 10.1097/ALN.0b013e318221fbbd
• RICCIO WICHT, Orbicia et al. Excess of serotonin affects neocortical pyramidal neuron migration. In: Translational Psychiatry, 2011, vol. 1, p. e47. doi: 10.1038/tp.2011.49
• TURCK, Natacha et al. A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage. In: Intensive Care Medicine, 2010, vol. 36, n° 1, p. 107-115. doi: 10.1007/s00134-009-1641-y
• BRINER, Adrian et al. Bilateral whisker trimming during early postnatal life impairs dendritic spine development in the mouse somatosensory barrel cortex. In: Journal of Comparative Neurology, 2010, vol. 518, n° 10, p. 1711-1723. doi: 10.1002/cne.22297
• GASCON, Eduardo, VUTSKITS, Laszlo, KISS, Jozsef Zoltan. The role of PSA-NCAM in adult neurogenesis. In: Advances in Experimental Medicine and Biology, 2010, vol. 663, p. 127-136. doi: 10.1007/978-1-4419-1170-4_8
• DURRMEYER, Xavier et al. Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data. In: Pediatric Research, 2010, vol. 67, n° 2, p. 117-127. doi: 10.1203/pdr.0b013e3181c8eef3
• BRINER, Adrian et al. Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis. In: Anesthesiology, 2010, vol. 112, n° 3, p. 546-556. doi: 10.1097/ALN.0b013e3181cd7942
• DE ROO, Mathias et al. Anesthetics rapidly promote synaptogenesis during a critical period of brain development. In: PLOS ONE, 2009, vol. 4, n° 9, p. e7043. doi: 10.1371/journal.pone.0007043
• RICCIO, Orbicia et al. Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6. In: Molecular psychiatry, 2009, vol. 14, n° 3, p. 280-90. doi: 10.1038/mp.2008.89
• VUTSKITS, Laszlo, HABRE, Walid. L'anesthesie a-t-elle un impact sur le developpement cerebral ? In: La presse médicale, 2009, vol. 38, n° 11, p. 1591-1596. doi: 10.1016/j.lpm.2009.07.013
• VUTSKITS, Laszlo et al. Adverse effects of methylene blue on the central nervous system. In: Anesthesiology, 2008, vol. 108, n° 4, p. 684-92. doi: 10.1097/ALN.0b013e3181684be4
• VUTSKITS, Laszlo et al. Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial. In: Neurochemical Research, 2008, vol. 33, n° 7, p. 1325-31. doi: 10.1007/s11064-007-9586-4
• DAYER, Alexandre et al. Recruiting new neurons from the subventricular zone to the rat postnatal cortex: an organotypic slice culture model. In: European Journal of Neuroscience, 2008, vol. 27, n° 5, p. 1051-60. doi: 10.1111/j.1460-9568.2008.06091.x
• GASCON, Eduardo, VUTSKITS, Laszlo, KISS, Jozsef Zoltan. The Role of PSA-NCAM in Adult Neurogenesis. In: Neurochemical Research, 2008. doi: 10.1007/s11064-008-9744-3
• VUTSKITS, Laszlo, GASCON, Eduardo, KISS, Jozsef Zoltan. Effects of ketamine on the developing central nervous system. In: Ideggyogyaszati Szemle, 2007, vol. 60, n° 3-4, p. 109-112.
• VUTSKITS, Laszlo et al. Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture. In: Toxicology, 2007, vol. 234, n° 3, p. 216-226. doi: 10.1016/j.tox.2007.03.004
• GASCON, Eduardo, VUTSKITS, Laszlo, KISS, Jozsef Zoltan. Polysialic acid-neural cell adhesion molecule in brain plasticity: from synapses to integration of new neurons. In: Brain Research Reviews, 2007, vol. 56, n° 1, p. 101-118. doi: 10.1016/j.brainresrev.2007.05.014
• GASCON, Eduardo et al. Potentially toxic effects of anaesthetics on the developing central nervous system. In: European Journal of Anaesthesiology, 2007, vol. 24, n° 3, p. 213-224. doi: 10.1017/S0265021506002365
• GASCON, Eduardo et al. PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival. In: Development, 2007, vol. 134, n° 6, p. 1181-1190. doi: 10.1242/dev.02808
• VAUDAN VUTSKITS, Geneviève et al. A role for atm in E-cadherin-mediated contact inhibition in epithelial cells. In: Breast Cancer Research and Treatment, 2006, vol. 99, n° 2, p. 143-53. doi: 10.1007/s10549-006-9195-y
• VUTSKITS, Laszlo et al. Anesthesia management in a young child with aromatic l-amino acid decarboxylase deficiency. In: Paediatric Anaesthesia, 2006, vol. 16, n° 1, p. 82-4. doi: 10.1111/j.1460-9592.2005.01605.x
• VUTSKITS, Laszlo et al. Effect of ketamine on dendritic arbor development and survival of immature GABAergic neurons in vitro. In: Review of Economic Dynamics, 2006, vol. 91, n° 2, p. 540-549. doi: 10.1093/toxsci/kfj180
• VUTSKITS, Laszlo et al. Les agents anesthésiques perturbent-ils le développement cérébral ? - Do anesthetics impair brain development? In: Archives de pédiatrie, 2006, vol. 13, n° 6, p. 777-779. doi: 10.1016/j.arcped.2006.03.106
• VUTSKITS, Laszlo et al. The polysialylated neural cell adhesion molecule promotes neurogenesis in vitro. In: Neurochemical Research, 2006, vol. 31, n° 2, p. 215-225. doi: 10.1007/s11064-005-9021-7
• VUTSKITS, Laszlo et al. Clinically relevant concentrations of propofol but not midazolam alter in vitro dendritic development of isolated gamma-aminobutyric acid-positive interneurons. In: Anesthesiology, 2005, vol. 102, n° 5, p. 970-976. doi: 10.1097/00000542-200505000-00016
• GASCON, Eduardo et al. Sequential activation of p75 and TrkB is involved in dendritic development of subventricular zone-derived neuronal progenitors in vitro. In: European Journal of Neuroscience, 2005, vol. 21, n° 1, p. 69-80. doi: 10.1111/j.1460-9568.2004.03849.x
• ZHANG, Huanxiang et al. A role for the polysialic acid-neural cell adhesion molecule in PDGF-induced chemotaxis of oligodendrocyte precursor cells. In: Journal of Cell Science, 2004, vol. 117, n° Pt 1, p. 93-103. doi: 10.1242/jcs.00827
• BARTANUSZ, V. et al. Local gamma-aminobutyric acid and glutamate circuit control of hypophyseotrophic corticotropin-releasing factor neuron activity in the paraventricular nucleus of the hypothalamus. In: European Journal of Neuroscience, 2004, vol. 19, n° 3, p. 777-782. doi: 10.1111/j.1460-9568.2004.03167.x
• CAHANA, Alex, VUTSKITS, Laszlo, MULLER, Dominique. Acute differential modulation of synaptic transmission and cell survival during exposure to pulsed and continuous radiofrequency energy. In: Journal of Pain, 2003, vol. 4, n° 4, p. 197-202. doi: 10.1016/s1526-5900(03)00554-6
• BARRAL-MORAN, M. J. et al. Oligodendrocyte progenitor migration in response to injury of glial monolayers requires the polysialic neural cell-adhesion molecule. In: Journal of Neuroscience Research, 2003, vol. 72, n° 6, p. 679-690. doi: 10.1002/jnr.10627
• VUTSKITS, Laszlo, GASCON, Eduardo, KISS, Jozsef Zoltan. Removal of PSA from NCAM affects the survival of magnocellular vasopressin- and oxytocin-producing neurons in organotypic cultures of the paraventricular nucleus. In: European Journal of Neuroscience, 2003, vol. 17, n° 10, p. 2119-2126. doi: 10.1046/j.1460-9568.2003.02660.x
• ZHANG, Huanxiang et al. VEGF is a chemoattractant for FGF-2-stimulated neural progenitors. In: The Journal of Cell Biology, 2003, vol. 163, n° 6, p. 1375-1384. doi: 10.1083/jcb.200308040
• VUTSKITS, Laszlo et al. PSA-NCAM modulates BDNF-dependent survival and differentiation of cortical neurons. In: European Journal of Neuroscience, 2001, vol. 13, n° 7, p. 1391-1402. doi: 10.1046/j.0953-816x.2001.01516.x
• KISS, Jozsef Zoltan et al. The role of neural cell adhesion molecules in plasticity and repair. In: Current Opinion in Neurobiology, 2001, vol. 36, n° 2-3, p. 175-184. doi: 10.1016/S0165-0173(01)00093-5
• MULLER, Dominique et al. Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus. In: Proceedings of the National Academy of Sciences, 2000, vol. 97, n° 8, p. 4315-4320. doi: 10.1073/pnas.070022697
• SPAHR-SCHOPFER, Isabelle et al. Differential neurotoxic effects of propofol on dissociated cortical cells and organotypic hippocampal cultures. In: Anesthesiology, 2000, vol. 92, n° 5, p. 1408-1417. doi: 10.1097/00000542-200005000-00032
• VUTSKITS, Laszlo et al. Magnocellular vasopressinergic neurons in explant cultures are rescued from cell death by ciliary neurotrophic factor and leukemia inhibiting factor. In: Neuroscience, 1998, vol. 87, n° 3, p. 571-582. doi: 10.1016/S0306-4522(98)00177-8