Justin Gainor
Associate Professor of Medicine at Harvard Medical School
Schools
- Harvard Medical School
Links
Biography
Harvard Medical School
Justin F. Gainor, MD is a medical oncologist in the Center for Thoracic Cancers at the Massachusetts General Hospital and an assistant professor of medicine at Harvard Medical School. In 2018, he was appointed director of targeted immunotherapy in the Henri and Belinda Termeer Center for Targeted Therapies at MGH. His major research interests have centered around two themes: targeted therapy and immunotherapy. Dr. Gainor has led multiple clinical trials evaluating novel targeted therapies for patients with oncogene-driven lung cancers, particularly those harboring chromosomal rearrangements involving anaplastic lymphoma kinase (ALK) and RET. In parallel, he has played an active role in uncovering the molecular mechanisms of resistance to targeted therapies in lung cancer. He believes that identifying such mechanisms of resistance can provide crucial insights into development of future targeted therapies and combination strategies.
More recently, Dr. Gainor has worked to transfer the same clinical-translational research framework pioneered in targeted therapies to the immunotherapy setting. His current work is investigating the role of novel immunotherapies and immunotherapy combinations in patients with oncogenic driver mutations, such as ALK rearrangements. Through careful insights into the immune landscape of such tumors, he hopes to extend the benefit of immunotherapies to these patient populations.
Research Interests
cancer immunotherapy; cancer treatment resistance; carcinoma non-small-cell lung; drug resistance neoplasm; gene rearrangement; immune checkpoint blockade; lung cancer; physician-patient relations; protein-tyrosine kinases; proto-oncogene proteins c-ret; receptor protein-tyrosine kinases
Companies
- Associate Professor Harvard Medical School (2021)
- Director, Center for Thoracic Cancers Massachusetts General Hospital (2019)
- Director, Targeted Immunotherapy Massachusetts General Hospital (2018)
- Thoracic Oncologist Massachusetts General Hospital (2013)
- Assistant Professor Harvard Medical School (2017 — 2021)
- Instructor Harvard Medical School (2013 — 2017)
- Hematology/Oncology Fellow DANA FARBER PARTNERS CANCER CARE INC (2011 — 2013)
- Internal Medicine Resident Massachusetts General Hospital (2008 — 2011)
Education
- Doctor of Medicine - MD Harvard Medical School (2004.09 — 2008.06)
- Bachelor's degree The Johns Hopkins University (2000.09 — 2004.06)
Videos
New Strategies in Lung Cancer: Innovations in Clinical Trials, Treatments, and Patient Care
How the Treatment Paradigm for EGFR+ Lung Cancer Will Transform
Immunotherapy at Mass General - the one hundred 2016
Advances in Immunotherapy at the Mass General Cancer Center
Dr. Gainor on Potential With BLU-667 in RET+ NSCLC
Dr. Gainor on the Evolving Lung Cancer Armamentarium
Cancer Immunotherapy Research Updates Panel at 2019 CRI Immunotherapy Patient Summit in Boston
Practical Considerations for Adjuvant vs. Neoadjuvant Immunotherapy in NSCLC
Justin Gainor Talks about Immunotherapy as Innovation
Approaches for Optimal Molecular Testing, Treatment, and Management of NSCLC
The Future of Tumor Testing
Dr. Gainor on Neoadjuvant Use of Biomarkers in Nonmetastatic Lung Cancer
2020 TTF RARE Mutations GAINOR Frontline Therapy for Uncommon Mutations
New Frontiers in Precision Immuno-Oncology
Summary of Immunotherapy: Justin Gainor, MD
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