John Tregoning

Science communication

I blog about science and academic careers. I have written for Nature, Science, Times Higher Education and The Guardian.

During the COVID19 lockdown, I wrote a weekly diary for the Nature Career Column.

I have been interviewed by Bloomberg, BBC Radio London, BBC Radio Scotland, BBC Breakfast, BBC online, The Independent, The Telegraph, The Sunday Telegraph, The Daily Mail and CGTN.

I have written a popular science book: Infectious

Contract research

I have experience of working with biotech companies to perform pre-clinical assessment of vaccines to RSV and influenza. This uses our well established infection models and we are open to further collaborations. We are open for new collaborations.

Selected Publications

Journal Articles

• Tregoning J, 2021, Coronavirus diaries: the COVID 19., Nature
• Tregoning JS, 2020, First human efficacy study of a plant-derived influenza vaccine, The Lancet, Vol:396, ISSN:0140-6736, Pages:1464-1465
• Tregoning JS, Brown ES, Cheeseman HM, et al., 2020, Vaccines for COVID-19, Clinical and Experimental Immunology, Vol:202, ISSN:0009-9104, Pages:162-192
• Tregoning J, 2020, Coronavirus diaries: to be a scientist, Nature, Vol:581, ISSN:0028-0836, Pages:226-226
• Turner P, Abdulla AF, Cole M, et al., 2019, Differences in nasal IgA responses to influenza vaccine strains after Live Attenuated Influenza Vaccine (LAIV) immunisation in children, Clinical and Experimental Immunology, Vol:199, ISSN:0009-9104, Pages:109-118
• Lindsey BB, Jagne YJ, Armitage EP, et al., 2019, Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study, Lancet Respiratory Medicine, Vol:7, ISSN:2213-2600, Pages:665-676
• Tregoning JS, Mallia P, 2019, Modulating airway glucose to reduce respiratory infections, Expert Review of Respiratory Medicine, Vol:13, ISSN:1747-6348, Pages:121-124
• Tregoning JS, Mallia P, Webber J, et al., 2018, Role of airway glucose in bacterial infections in chronic obstructive pulmonary disease, Journal of Allergy and Clinical Immunology, Vol:142, ISSN:0091-6749, Pages:815-823.e6
• Tregoning J, 2018, How will you judge me if not by impact factor?, Nature, Vol:558, ISSN:0028-0836, Pages:345-345
• Groves HT, Cuthbertson L, James P, et al., 2018, Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota, Frontiers in Immunology, Vol:9, ISSN:1664-3224
• Groves HT, McDonald JU, Langat P, et al., 2018, Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy, Frontiers in Immunology, Vol:9, ISSN:1664-3224
• Tregoning J, 2018, From parade ground to PI., Science, Vol:359, Pages:362-362
• Vogel AB, Lambert L, Kinnear E, et al., 2017, Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses., Molecular Therapy, Vol:26, ISSN:1525-0016, Pages:446-455
• Kinnear E, Lambert L, McDonald JU, et al., 2017, Airway T cells protect against RSV infection in the absence of antibody, Mucosal Immunology, Vol:11, ISSN:1933-0219, Pages:249-256
• Gould VMW, Francis JN, Anderson KJ, et al., 2017, Nasal IgA provides protection against human influenza challenge in volunteers with low serum influenza antibody titre, Frontiers in Microbiology, Vol:8, ISSN:1664-302X
• McDonald JU, Zhong Z, Groves HT, et al., 2017, Inflammatory responses to influenza vaccination at the extremes of age., Immunology, Vol:151, ISSN:0019-2805, Pages:451-463
• Tregoning J, 2017, No researcher is too junior to fix science, Nature, Vol:545, ISSN:0028-0836, Pages:7-7
• Mcdonald J, Kaforou M, Clare S, et al., 2016, A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease, Msystems, Vol:1, ISSN:2379-5077
• Gill SK, Hui K, Farne H, et al., 2016, Increased airway glucose increases airway bacterial load in hyperglycaemia, Scientific Reports, Vol:6, ISSN:2045-2322
• Russell RF, McDonald JU, Lambert L, et al., 2016, Use of the microparticle Nano-SiO2 as an adjuvant to boost vaccine immune responses in neonatal mice against influenza., Journal of Virology, Vol:90, ISSN:1098-5514, Pages:4735-4744
• Siggins MK, Gill SK, Langford PR, et al., 2015, PHiD-CV induces anti-Protein D antibodies but does not augment pulmonary clearance of nontypeable Haemophilus influenzae in mice, Vaccine, Vol:33, ISSN:1873-2518, Pages:4954-4961
• Kinnear E, Caproni LJ, Tregoning JS, 2015, A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging, PLOS One, Vol:10, ISSN:1932-6203
• Russell RF, McDonald JU, Ivanova M, et al., 2015, Partialattenuation of respiratory syncytial virus with a deletion of a small hydrophobic gene Is associated with elevated interleukin-1β responses, Journal of Virology, Vol:89, ISSN:1098-5514, Pages:8974-8981
• Walters AA, Kinnear E, Shattock RJ, et al., 2014, Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines, Gene Therapy, Vol:21, ISSN:1476-5462, Pages:645-652
• Tregoning JS, Wang BL, McDonald JU, et al., 2013, Neonatal antibody responses are attenuated by interferon-gamma produced by NK and T cells during RSV infection, Proceedings of the National Academy of Sciences of the United States of America, Vol:110, ISSN:0027-8424, Pages:5576-5581
• Tregoning JS, Kinnear E, 2014, Using Plasmids as DNA Vaccines for Infectious Diseases., Plasmids: Biology and Impact in Biotechnology and Discovery, ASMscience, ISBN:9781555818975