James Houston

Overview

Director of Centre for Applied Pharmacokinetic Research and Head of Pharmaceutical Sciences in Manchester Pharmacy School .

Biography

Brian obtained his BSc, PhD and DSc from the Universities of London (Queen Mary College), Surrey and Manchester, respectively. He is currently Professor of Drug Metabolism and Pharmacokinetics within Manchester Pharmacy School. His research is sponsored by a number of sources including the pharmaceutical industry, BBSRC, DoH and the EU.

Brian is Director of the Centre for Applied Pharmacokinetic Research within Manchester Pharmacy School. This involves five faculty members and supports twenty research staff. As a consortium it operates in collaboration with, and financially supported by international pharmaceutical companies. All research is generic and involves the prediction of human pharmacokinetics.

In recent years he has been particularly active through his research and numerous conference presentations in promoting the use of in vitro and in silico systems for predicting human metabolism and pharmacokinetics. Brian is a member of the editorial boards of several scientific journals, has experience on national science funding bodies and is a consultant to a number of pharmaceutical companies.  He is a Fellow of the American Association of Pharmaceutical Scientists (AAPS) and received the International Society for Study of Xenobiotics (ISSX) 2014 European Scientific Achievement Award.

He has supervised over 60 graduate students.  His research publications in the area of drug metabolite kinetics in vivo and  in vitro exceed 200 and are highly cited.  He was named as a Thomson Reuters Highly Cited Researcher in 2015 - ranking among the top 1% most cited scientists in his subject field (Pharmacology & Toxicology) earning him the mark of exceptional impact.