Catherine Klapperich, Ph.

Associate Chair for Graduate Studies, Biomedical Engineering Associate Professor, Biomedical Engineering Associate Professor, Mechanical Engineering at Boston University

Schools

  • Boston University

Links

Biography

Boston University

Dr. Catherine Klapperich is a Kern Innovation Faculty Fellow and an Associate Professor of Biomedical Engineering at Boston University. She also holds appointments in the Division of Materials Science and Engineering and the Department of Mechanical Engineering. She is the Director of the Laboratory for Diagnostics and Global Healthcare Technologies and a member of theCenter for Nanoscience and Nanotechnology. In 2012, she became the director of the newly formed NIH Center for Future Technologies in Cancer Care (FTCC) at BU.

Before coming to Boston, Dr. Klapperich was a Postdoctoral Fellow at Lawrence Berkeley Laboratory in the lab of Dr. Carolyn Bertozzi, and was a Senior Research Scientist at Aclara Biosciences in Mountain View, CA. She earned her Ph.D. in Mechanical Engineering in 2000 from the University of California, Berkeley with Drs. Lisa Pruitt and Kyriakos Komvopoulos; her M.S. in Engineering Sciences from Harvard University and her B.S. in Materials Science and Engineering from Northwestern University.

Dr. Klapperich’s research is focused on engineering medical devices for use in low resource settings and at the point of care. Current projects are focused on disposable microfluidic diagnostics that incorporate on-board sample preparation and on minimally instrumented devices to enable molecular diagnostics. Her work includes diagnostics for infectious diarrhea, respiratory infections, HIV and other sexually transmitted diseases. These devices have been tested in Nicaragua and Kenya. Other work in the lab is focused on the design and deployment of devices to enable systems biology approaches to studying complex diseases including TB.

Dr. Klapperich’s lab is funded by grants from the NIH, DOD, CIMIT and the Coulter Foundation. In 2010, she was an invited participant in the National Academies of Engineering Frontiers of Engineering conference held in Agra, India. She serves on the editorial board of Biomedical Microdevices and is an active participant in both national and international research conferences.

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Cases

S scientists accuse Turkish researcher of spiriting away their idea — and claiming it as her own

March 15, 2017

STAT News Catherine Klapperich, College of Engineering Catherine Klapperich was at home one night recently when she pulled up the news coverage… Expert quote: ““Seeing it on TV, it’s so visceral. You click on the link, and I gasped, like, ‘Oh my gosh, how can this be?’” said Klapperich, a biomedical engineer at Boston University.” […]

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Biotech World Abuzz Over Questions About Theranos Technology

October 20, 2015

WBUR “Radio Boston” Catherine Klapperich, College of Engineering Imagine that, with a simple prick of the finger, you could test your blood for more than 200 different things — including for cancer and cholesterol… Listen to audio of expert Catherine Klapperich

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Commentary: Despite Doubts Raised On Theranos, Great Need For Quick Diagnoses

October 19, 2015

WBUR “CommonHealth” Co-written by Catherine Klapperich, College of Engineering The recent news that the multibillion-dollar health care startup Theranos has potentially been overselling its ability to perform fast, “point-of-care” diagnostic testing using only a drop of a patient’s blood is disappointing to many test developers and health care providers… View full article by expert Catherine […]

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Quicker test in the works for HIV viral load

June 26, 2015

Futurity News Catherine Klapperich, College of Engineering Catherine Klapperich’s lab creates point-of-care diagnostics—tools, such as a pregnancy test stick, that doctors and regular people can use to immediately test for conditions like high cholesterol or diagnose illnesses like strep throat… View full article featuring expert Catherine Klapperich  

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Power-free nucleic acid extraction device

June 6, 2013

Chemistry World Catherine Klapperich, College of Engineering HIV RNA has been successfully extracted from human blood using a portable device that does not need electrical power to work… Expert quote: “It allows task shifting of the nucleic acid extraction step to the site of the blood draw.” View full article

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Microfluidic chips offer a SMART-er way to detect flu

June 13, 2012

Nature Catherine Klapperich, College of Engineering Tracking influenza outbreaks quickly and cheaply could get a whole lot easier thanks to a number of experimental devices that can accurately detect viral strains in an hour or so… View article

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Microfluidic chip to quickly diagnose the flu

March 30, 2012

CNET News Catherine Klapperich, College of Engineering During the H1N1 flu pandemic of 2009, which spread across more than 200 countries and killed more than 18,000 people, it became clear that flu diagnosis was often taking too long and resulting in frequent false negatives… View article

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Scientists Develop Disposable Microfluidic Chip for Flu Detection

March 29, 2012

AZoNano Catherine Klapperich, College of Engineering A research team led by Catherine Klapperich from the Boston University has devised a disposable microfluidic chip, which is a precise, inexpensive, rapid point-of-care device that could serve as an efficient tool for clinicians to rapidly diagnose pandemic and seasonal influenza strains, thus restricting infection outbreaks… View article

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Boston University researchers develop microfluidic chip to stem flu outbreaks

March 27, 2012

Science Codex Catherine Klapperich, College of Engineering The H1N1 flu pandemic in 2009 underscored weaknesses in methods widely used to diagnose the flu, from frequent false negatives to long wait times for results… View article

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