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Zurich School for Continuing Education

Continuous Chromatography for Biotherapeutics

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This course provides an introduction to continuous chromatography with hands-on practice with novel capture and polishing processes for biomolecules. Attendees will acquire the basic tools to design, run and evaluate multicolumn processes and to quantify these improvements.

Additional information

As the least complex of all multi-column processes, the workshop is focused on twin column chromatography.

  • Introduction to continuous chromatography for bio-molecules
  • Theory of multi-column chromatography
  • Design of multi-column chromatography processes
  • Hands-on training on twin column equipment capture and polishing applications
  • Process performance evaluation and scale-up
  • note: This workshop does not cover 4-zone SMB, chiral and small molecule separations.

Who should attend

This course is aimed at industry and academic separation scientists and bioprocess development engineers who already have some familiarity with single column chromatography and who want to broaden their understanding of chromatographic processes and look at new and more efficient ways to separate. Only participants with industry and academic affiliation can be accepted, no vendors.


Massimo Morbidelli has been full Professor of Chemical Reaction Engineering in the Chemical Engineering Laboratory since November 1, 1995. Prof. Morbidelli was born on March 12, 1954 in Vercelli, Italy. He took his degree in chemical engineering at the Politecnico, Milan, in 1977 and earned his ...
Thomas Müller-Späth, Dr. sc. ETH, Dipl.-Ing., a founder, has more than 10 years of R&D and operational experience in the biopharmaceutical industry in Germany, Switzerland and the USA. Thomas is the co-inventor of several patents and has published numerous articles in journals. Besides his op...
Paolo Arosio received his master degree in Chemical Engineering from the Politecnico di Milano in 2007, and his doctoral degree from ETH Zurich in 2011. After his doctoral studies he moved to the group of Prof. Tuomas Knowles at the Department of Chemistry at the University of Cambridge, UK, wher...

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